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Multiple Choice

Which symptom is a cardinal sign of inflammation?

Swelling, or edema, is a classic sign of inflammation. When inflammation kicks in, chemical mediators make blood vessels leakier, so fluid escapes into the surrounding tissue. That fluid accumulation causes the area to swell—this swelling is the “tumor” sign historically listed among the cardinal signs. Redness and warmth come from increased blood flow, and fever is a systemic response, but the persistent tissue swelling is the hallmark local sign among the options. So edema best fits as a cardinal sign of inflammation.

Swelling, or edema, is a classic sign of inflammation. When inflammation kicks in, chemical mediators make blood vessels leakier, so fluid escapes into the surrounding tissue. That fluid accumulation causes the area to swell—this swelling is the “tumor” sign historically listed among the cardinal signs. Redness and warmth come from increased blood flow, and fever is a systemic response, but the persistent tissue swelling is the hallmark local sign among the options. So edema best fits as a cardinal sign of inflammation.