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Multiple Choice

Karyotype with at least two X chromosomes and a Y chromosome in each cell defines which syndrome?

A male with an extra X chromosome in addition to a Y is described by XXY, which is Klinefelter syndrome. This pattern—two Xs and a Y in each cell—defines the condition, distinguishing it from Turner syndrome (one X and no Y), Triple X syndrome (three Xs and no Y), and Down syndrome (an extra chromosome 21, not a sex chromosome).

A male with an extra X chromosome in addition to a Y is described by XXY, which is Klinefelter syndrome. This pattern—two Xs and a Y in each cell—defines the condition, distinguishing it from Turner syndrome (one X and no Y), Triple X syndrome (three Xs and no Y), and Down syndrome (an extra chromosome 21, not a sex chromosome).