Failure of neural tube closure during fetal development is associated with which disorder?

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Multiple Choice

Failure of neural tube closure during fetal development is associated with which disorder?

Neural tube closure occurs early in pregnancy, during the third to fourth week. When this process fails, defects along the spine or skull can arise. Spina bifida is a defect where the posterior neural tube does not close properly, leaving a gap in the spinal column and sometimes exposing the meninges or spinal cord. Anencephaly results from failure of closure at the anterior end of the neural tube, causing severe underdevelopment of the brain and skull. Encephalocele involves herniation of brain tissue through a skull defect. Meningitis, meanwhile, is an infection of the brain and spinal cord coverings, not a neural tube closure defect. Given this, the disorder associated with failure of neural tube closure is spina bifida.

Neural tube closure occurs early in pregnancy, during the third to fourth week. When this process fails, defects along the spine or skull can arise. Spina bifida is a defect where the posterior neural tube does not close properly, leaving a gap in the spinal column and sometimes exposing the meninges or spinal cord. Anencephaly results from failure of closure at the anterior end of the neural tube, causing severe underdevelopment of the brain and skull. Encephalocele involves herniation of brain tissue through a skull defect. Meningitis, meanwhile, is an infection of the brain and spinal cord coverings, not a neural tube closure defect. Given this, the disorder associated with failure of neural tube closure is spina bifida.

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