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Multiple Choice

A 51-year-old woman with chronic intermittent epigastric pain relieved by ingestion of food most likely has which condition?

Pain that is relieved by eating is a classic clue for a duodenal ulcer, a type of peptic ulcer disease. In this condition, acid irritates the duodenal mucosa, and meals help buffer the acid and increase mucus and bicarbonate production, producing temporary relief from pain. This pattern contrasts with gastric ulcers, where pain often worsens with meals because the damaged stomach lining is exposed to food-related acid. GERD typically presents with heartburn and regurgitation rather than episodic epigastric pain relieved by food. So the described pattern most strongly points to a duodenal ulcer.

Pain that is relieved by eating is a classic clue for a duodenal ulcer, a type of peptic ulcer disease. In this condition, acid irritates the duodenal mucosa, and meals help buffer the acid and increase mucus and bicarbonate production, producing temporary relief from pain. This pattern contrasts with gastric ulcers, where pain often worsens with meals because the damaged stomach lining is exposed to food-related acid. GERD typically presents with heartburn and regurgitation rather than episodic epigastric pain relieved by food. So the described pattern most strongly points to a duodenal ulcer.